Like I said before, I'm not used to 2 QB leagues, but based on how they are valued in your league, I think you have to consider keeping three of Brady, Wentz, Smith and Mariota. Also, I know that in keeper leagues that early R1 draft picks aren't as valuable as in standard, but I would at least consider keeping one of Collins and McKinnon and tossing back Zeke, unless you think he's a top 2 RB, which I don't. If it were me, it would be Thomas, Smith, Wentz, Mariota, Collins.