You should definitely take into account where a guy plays his home games, but too often people look at home/away splits, take the away #s and consider that a guy's true ability. Additionally, there isn't just one factor in looking at the splits. You have the hitter's park situation, but it's also a comfort level. Players shouldn't be penalized for being much better when playing in their home city. The entire discrepancy in Santo's #s can't be chalked up to Wrigley's small gaps. He couldn't have hit that many HRs in the first few rows. There's also something to be said for a hitter adapting his game to fit his home park. If Santo saw the value in getting under a pitch and letting the wind carry it out, then good for him. Again that's not to say to discount the Wrigley in the 60s factor, but I don't think it's as big of an issue as his detractors make it out to be.