well, it would help in large part to actually see your team when answering these questions, but here's what I've got: 1. For me, I always like to grab at least one stud starting pitcher early in the rounds (rarely the first round, personally). This year I grabbed Johan Santana with my second pick. After that, starting pitchers can be kind of fickle. For example any given week Carlos Zambrano has a decent probability of giving you a worse start than, say, Jason Marquis. Obviously, with the better pitcher you are more likely to get a good start, so you do want to try to fill your team with the best pitchers possible while at the same time paying mind to your stats. That is, if you draft someone like Matt Cain who will give you good ERA, Whip, and K numbers, you're still going to lose out on wins because he plays on the freaking Giants. Long story short, it's a balance. Better pitchers always give you the best shot at getting points. That said, if you draft someone like a Johan Santana who gives you a ton of K's and a low ERA you are better able to afford a ted lilly type who won't give you as good of an ERA but is more likely to get wins than say a Matt Cain type, even though he may not be as good of a pitcher, simply because of the team he's on. As for relief pitchers, I rarely keep more relievers than i have spots for them. This allows me the maximum amount of starts from my starters (who log more innings, thus more opportunities for strikeouts - plus they are more likely to get wins). Relievers are really good for keeping your ERA and WHIP down while adding some extra K's, but i don't load my staff with them. 2. This one completely depends on your team. David Price could be a goldmine, but if you don't have the extra bench spots to hold him until he comes up then maybe Gregg would be a better option - especially if your closer situation is poor. 3. Again, depends on the team. If you already have a good closer or two, then take the really good middle reliever (say, marmol) who will add you a bunch of K's and low ERA numbers. But if you need a closer, i'd probably take that.