i haven't had any success at all with it "curing" hangovers but it has definitely helped as a preventative measure. (pedialyte, that is...haven't done the sprite thing) ok, well, cure is a bit dramatic I suppose. But it helps with the dehydration which causes a lot of the problems, also sprite has been shown to help metabolize ethanol quicker by your liver. try it! my roomate used to add 2 advil to the concoction, but to each their own the one thing that did NOT work for me, ever - was coffee. it just made me feel hyper while feeling crappy at the same time, and made me pee more, which seemed contradictory to everything