I played it a bit around launch, but had to set it aside for personal reasons. Now that they've put a couple years of updates into it, it is considerably less buggy. I only ran into a couple of NPCs stuck in T-poses this time around, and had my motorcycle get stuck upside down (with me on it) just once. Other than that, it was pretty smooth sailing.
This game could have really been something special if it had been managed better. But it was a buggy mess when it came out, and the performance was a nightmare. Both of those issues could have probably been avoided if they weren't trying to drag last-gen along for the ride.
The game itself is a blast. I still maintain that The Heist is one of the all-time great missions in video game history.
The game is at its best when it's got these crazy set pieces. And there are a lot of good ones. The side quests add a lot of flavor as well (exploding penis implant, anyone?). But the gigs [smaller side quests] are pretty repetitive. Could have gone for fewer of those if it meant more development time on the quests. Lore was good. And Johnny Silverhand is great.
There's a new DLC coming out in a few months. For those of you who haven't checked out the game yet, that might be a good time to do so.